METHOD OF USE IN THERAPY Russian patent published in 2016 - IPC A61K39/00 A61P37/02 C07K14/47 

Abstract RU 2579659 C2

FIELD: bioengineering.

SUBSTANCE: invention relates to use of the antigenic compound including the antigenic peptide produced from amyloid protein or amyloid-like protein for medical treatment of the disease, state or distress due to or linked with the said protein in population of patients suffering from insufficiency of T-cells during induction of the immune response. The said antigen peptide is modified by lipophilic or hydrophobic part of the molecule, that makes easier insertion to the lipidic double layer of the liposomal carrier/adjuvant, and is presented in form of frequently repeated matrix on surface of the liposome. The said antigen compound is used for medical treatment of the disease, state or distress due to or as result of amyloid protein or amyloid-like protein in amount sufficient for induction of the immune response independent from T-cells.

EFFECT: invention permits use of the said antigen compound as per new medical application, namely, for medical treatment of the diseases, when it is desirable to generate immune bodies independent from T-helper cells, for example, at animals or people with the immunodeficiency or with autoimmune diseases, such as Alzheimer's disease.

51 cl, 22 dwg, 6 tbl, 6 ex

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RU 2 579 659 C2

Authors

Andrea Pfajfer

Andreas Mus

Marija Pilgren

Dates

2016-04-10Published

2010-03-18Filed