FIELD: medicine. SUBSTANCE: method deals with application of thermolabile enterotoxin [EtxB] and their mixtures of gangliozide GM-1(GM-1)- binding activity for treating or preventing autoimmune diseases. The predominance is in the fact that the mentioned subunits induce activation of B-cells due to binding with GM-1 gangliozide receptors. EFFECT: higher efficiency of therapy. 3 cl, 11 dwg, 4 ex, 3 tbl
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