PEPTIDE PRO-DRUGS OF AMIDE GLUCAGON SUPERFAMILY Russian patent published in 2016 - IPC C07K14/605 A61K38/26 A61K47/48 

Abstract RU 2580317 C2

FIELD: medicine.

SUBSTANCE: invention refers to pro-drug preparations consisting of peptides of the glucagon superfamily, wherein the above peptide of the glucagon superfamily has been modified by dipeptide attaching to the peptide of the glucagon superfamily by an amide bond.

EFFECT: pro-drugs described above have a long half-life and are able to transform into an active form in the physiological environment by means of a non-enzymatic reaction induced by chemical instability.

16 cl, 18 dwg, 19 tbl, 19 ex

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RU 2 580 317 C2

Authors

Dimarchi Richard D.

Kou Binbin

Dates

2016-04-10Published

2011-06-14Filed