FIELD: medicine.
SUBSTANCE: present invention relates to exendin-4 derivatives that activate the glucagon-like peptide 1 (GLP-1) receptor and glucose-dependent insulinotropic polypeptide (GIP), and optionally glucagon receptor (GCG), their use to treat metabolic syndrome disorders, including diabetes and obesity, and to reduce excess food intake.
EFFECT: for the treatment of metabolic syndrome disorders, including diabetes and obesity, and to reduce excessive food intake.
16 cl, 8 dwg, 9 ex, 11 tbl
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Authors
Dates
2018-05-03—Published
2013-12-19—Filed