FIELD: pharmacology.
SUBSTANCE: invention relates to new derivatives of trans-2-decenoic acid in formula (1′), or pharmaceutically acceptable salts thereof, in which values for groups Y′, W′ are defined in the formula of invention. Invention also relates to a pharmaceutical agent, having activity as neurotrophic factor, and/or easing effect on a side effect caused by introduction of anticancer agents containing derivative of trans-2-decenoic acid in formula (1), or its pharmaceutically acceptable salt as an active ingredient, in which values for groups Y and W are defined in the formula of invention.
EFFECT: pharmaceutical agent has a sufficiently wide range of application, such as a preventive or therapeutic agent for dementia, Alzheimer's disease, Parkinson's disease, depression and so on, medical or reducing agent for spinal injury or relieving agent for side effect caused by introduction of anticancer agents.
(1′) 
(1)
23 cl, 9 dwg, 68 ex, 2 ex
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