PHARMACEUTICAL COMPOSITION OF STATINS WITH PREBIOTIC FOR THERAPY OF HYPERCHOLESTEREMIA AND HYPERLIPIDEMIA Russian patent published in 2016 - IPC A61K31/4025 A61K31/47 A61K31/7016 A61K31/702 A61K31/732 A61K31/733 A61K31/719 A61K31/22 A61P9/00 

Abstract RU 2591079 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention represents a pharmaceutical composition for treating hypercholesteremia, triglyceridemia, ischemic heart disease (IHD) and prevention of myocardial infarction, stroke, atherosclerosis and reducing risk of unfavourable action of statins on blood glucose level, including, at least two active components, one component selected from group of statins: atorvastatin, lovastatin, Pravastatin, rosuvastatin, simvastatin, fluvastatin, pitavastatin, and second component is selected from group of prebiotics: xylitol, sorbitol, lactitol, lactulose, lactosucroze, melibioze, xylobioze, stachyose, raffinoze or galactooligosaccharide, maltooligosaccharide, xylooligosaccharide, isomalto-oligosaccharide, gentioligosaccharide, or arabinogalactan, pullulan, wherein components of composition are taken in certain proportions, mg.

EFFECT: invention provides efficient fixed combined preparation, reducing risk of diabetes mellitus, developing statins with underlying administration in therapy of such conditions as hypercholesterolemia, triglitzeridemia, ischemic heart disease, prevention of myocardial infarction, stroke and atherosclerosis, as well as solving problems of developing class-specific side effects of statins on carbohydrate metabolism and function of pancreas.

4 cl, 4 dwg, 6 ex

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RU 2 591 079 C2

Authors

Dikovskij Aleksandr Vladimirovich

Zakirova Svetlana Anatolevna

Matyushenok Aleksandr Viktorovich

Dates

2016-07-10Published

2014-12-10Filed