FIELD: medicine; pharmacy.
SUBSTANCE: first version implies that pharmaceutical formulation contains antibiotic and prebiotic - oligosaccharide selected from: fructooligosaccharides, galactooligosaccharides, xylooligosaccharides, maltooligosaccharides and isomaltooligosaccharides by degree of polymerization from 2 to 10, and particles sizes up to 0.3 mm and purity not less than 95%, and antibiotic with particles sizes from 20 to 200 mcm; antibiotic and oligosaccharide are included in mass proportion from 1:1 to 1:100 respectively. Second version implies that pharmaceutical formulation contains powder antibiotic with particles from 20 to 200 mcm selected from: beta-lactamase, including combinations of beta-lactams and bacterial beta-lactamases inhibitors; azalides, fluoroquinolones, amphenicoles, glycopeptides, ansamicynes, nitrofurans, phosphonic acid derivatives, cycloserine, trimetoprym, and as a prebiotic - powder oligosaccharide by degree of polymerization from 2 to 10, particles sizes up to 0.3 mm and purity not less than 95%; antibiotic and oligosaccharide are included in mass proportion from 1:1 to 1:100 respectively; mentioned compositions are intended for oral introduction and applied for bowel disbios prevention caused by antibiotic therapy.
EFFECT: stimulates lactobacilli and bifidus bacteria action.
4 cl, 9 ex
