METHODS FOR IMPROVING PHARMACOKINETICS Russian patent published in 2016 - IPC A61K31/404 

Abstract RU 2591830 C2

FIELD: medicine.

SUBSTANCE: group of inventions discloses a method of treating hepatitis C virus infection in patients in need of such treatment comprising administering to a patient in need thereof a compound of formula I,

free base or pharmaceutically acceptable salt thereof, and a cytochrome P450 monooxygenase inhibitor or pharmaceutically acceptable salt thereof, cytochrome P450 monooxygenase inhibitor is ritonavir or pharmaceutically acceptable salt thereof, as well as pharmaceutical composition and a kit for treating viral hepatitis C.

EFFECT: using present group of inventions reduces production of reactive metabolites.

3 cl, 2 tbl, 1 ex

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RU 2 591 830 C2

Authors

Tren Dzhonatan K.

Dates

2016-07-20Published

2010-04-22Filed