FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to immunology, and can be used for producing of chimeric immunoglobulin preparation with specific antiviral or antibacterial effect. Chimeric immunoglobulin preparation contains immune proteins from milk and/or colostrum from immunized cows and stabilizing additives. Chimeric partially humanized bovine secretory immunoglobulin A (S-IgA) is used as immune protein, in which bovine secretory component is substituted by recombinant or donor human secretory component.
EFFECT: using this composition allows to create high-purity immunoglobulin preparation based on S-IgA with reduced immunogenicity and reactogenicity suitable for oral, parenteral and local adminstration.
3 cl, 5 ex
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Authors
Dates
2016-10-10—Published
2015-07-16—Filed