METHOD FOR DISSOLUTION TESTING OF SOLID COMPOSITIONS CONTAINING DIGESTIVE ENZYMES Russian patent published in 2016 - IPC A61K38/46 G01N33/15 

Abstract RU 2602183 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method of measuring the amount of digestive enzymes released from the solid composition in the medium of dissolution, by fluorescent spectroscopy. Proposed method consists in the fact that a pancrelipase solid composition is added to the first medium dissolution, having pH from approximately 1 to approximately 4.5, then the suspension is transferred into the second medium dissolution, having pH from approximately 5 to approximately 6.8.

EFFECT: then provide release of digestive enzymes sample aliquots of medium dilution is carried out and removal of readings of fluorescence calculating the amount of released digestive enzymes.

19 cl, 5 dwg, 6 tbl, 12 ex

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RU 2 602 183 C2

Authors

Latino Massimo

Ghidorsi Luigi

Ortenzi Giovanni

Dates

2016-11-10Published

2012-08-08Filed