FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmacology and medicine, and represents a composition for treating and preventing a disorder related to digestive enzyme insufficiency, containing a set of coated particles; each said particle comprises a enteric-coated core wherein the core contains pancrelipase and the enteric coating contains 10-20 wt % of at least one enteric-coated polymer and 4-10 wt % of talc wherein said wt % are calculated from total weight of the coated particles and wherein the coated particles show pancrelipase enzymatic activity loss by no more than approximately 25% after 6 months of accelerated stability test.
EFFECT: invention provides enzyme activity stability.
47 cl, 14 ex, 35 tbl
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