COMPOUNDS AND COMPOSITIONS FOR STABILISATION OF HYPOXIA INDUCED FACTOR-2 ALPHA AS METHOD OF CANCER MEDICAL TREATMENT Russian patent published in 2016 - IPC C07D213/16 A61K31/4412 A61P35/00 

Abstract RU 2602498 C2

FIELD: bioengineering.

SUBSTANCE: invention relates to the use of the compound having formula

to stabilise a hypoxia induced factor-2 alpha (HIF-2α), for the reduced regulation of phosphoglycerate kinase (PGK) in a cell, and for the increased regulation of the release from the cell of a dissoluble receptor-1 of a vascular endothelial growth factor (sVEGF-1).

EFFECT: higher efficiency of the compositions use.

13 cl, 15 dwg, 1 tbl, 5 ex

Similar patents RU2602498C2

Title Year Author Number
PROLYL HYDROXYLASE INHIBITORS 2010
  • Gardner Dzhozef Kh.
  • Shalvits Robert
RU2518071C2
METHOD FOR REDUCING MULTI-DRUG RESISTANCE WITH USING INOSITOL TRIPYROPHOSPHATE 2010
  • Nikolau Iv Klod
  • Len Zhan-Mari
  • Kieda Klodin
RU2563127C2
METHODS FOR INCREASING STABILISATION OF HYPOXYA INDUCED FACTOR-1 ALPHA 2010
  • Shalvits Robert
  • Gardner Dzhozef Kh.
RU2521251C2
PROLYL HYDROXYLASE INHIBITORS AND APPLICATION METHODS THEREOF 2007
  • Kavamoto Richard Masaru
  • Bojer Anzhelik San
  • Grejz Kennet Donal'D
  • Evdokimov Artem G.
  • Vu Shehndeh
  • Varshakun Namal Chitranga
RU2429226C9
COMPOSITIONS AND METHODS OF TREATING ANAEMIA 2014
  • Shalvits Robert
  • Khartman Sharlott
  • Bach Akshaj
  • Shalvits Isaiya
  • Yanush Dzhon
  • Gardner Dzhozef
RU2705206C2
ANGIOGENESIS INHIBITION 2008
  • Ferrara Napoleon
  • Shodzhejn Farbod
  • U Sjumin'
  • Chzhun Tsujlin
RU2471498C2
INHIBITION OF DISSEMINATION OF TUMOUR USING Bv8 OR G-CSF ANTAGONISTS 2010
  • Ferrara Napoleon
  • Kovanetts Martsin Leshek
RU2567803C2
USE OF NOX INHIBITORS FOR TREATMENT OF CANCER 2018
  • Vizel, Filipp
  • Khajts, Freddi
  • Tomas, Garet
  • Khanli, Kristofer
  • Ford, Kirsti
RU2780354C2
BENZOQUINONE E3330 DERIVATIVE IN COMBINATION WITH CHEMOTHERAPEUTIC AGENTS FOR TREATING CANCER AND ANGIOGENESIS 2008
  • Kelli Mark R.
RU2510270C2
ANTISENSE OLIGONUCLEOTIDES TO HIF-1-ALPHA 2017
  • Chung, Shin
  • Jung, Daram
  • Cho, Bongjun
  • Yoon, Heungsik
  • Jang, Kangwon
RU2753517C2

RU 2 602 498 C2

Authors

Shalvitz Robert

Marsh Klej

Roda Dzhuli

Jubenk Timoti

Dates

2016-11-20Published

2012-06-05Filed