PROLYL HYDROXYLASE INHIBITORS Russian patent published in 2014 - IPC C07D401/06 A61K31/497 A61P17/02 A61P37/00 A61P43/00 

Abstract RU 2518071 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compound of formula , where Z stands for phenyl, substituted with 1-5 halogen atoms, selected from fluorine and chlorine; R4 stands for C1-C4-alkyl with linear chain or C3-C4-alkyl with branched chain; or to its pharmaceutically acceptable salt. Invention also relates to pharmaceutical composition, inhibiting prolyl hydroxylase activity, based on said compounds.

EFFECT: obtained are novel compounds and based on them pharmaceutical composition, which can be applied in medicine for treatment of diseases, associated with immune response of organism.

18 cl, 20 dwg, 8 tbl, 13 ex

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RU 2 518 071 C2

Authors

Gardner Dzhozef Kh.

Shalvits Robert

Dates

2014-06-10Published

2010-11-05Filed