METHOD OF PRODUCING AGENT, BINDING WITH PRE-VASOPRESSIN OR ITS FRAGMENTS Russian patent published in 2017 - IPC G01N33/68 G01N33/74 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and method of producing binding agent or mixture of binding agents, capable to bind with epitope, contained in amino acid sequence, corresponding to C-end part of pre-vasopressin, consisting of amino acids 146-163, but not containing amino acid 164, where said method includes steps of producing binding agent with help of forming agent; determination binding ability of binding agent with amino acid sequence with length of at least 12 amino acids, contained in amino acid sequence, corresponding to C-end part, but not containing amino acid 164 of pre-vasopressin; selection of binding agent from multitude of binding agents. Group of inventions also relates to forming agent for producing binding agent or mixture of binding agents; application of binding agent for qualitative or quantitative detection of pre-vasopressin or its fragments in biological sample.

EFFECT: group of inventions provides qualitative or quantitative detection of pre-vasopressin or its fragments in biological sample.

20 cl, 1 ex, 5 dwg, 2 tbl