FIELD: pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutics. Oral pharmaceutical composition is described in form of prolonged release for treating neurodegenerative disease or damage of nervous system. Above composition contains R(+)-N-propargyl-1-aminoindan (rasagiline) as active substance. Composition contains pellets with prolonged release and pharmaceutically acceptable carrier. Said pellet includes: I) inert core of pellet; II) layer with active substance, polyvinyl pyrrolidone and talc; III) optionally insulating layer with polyvinyl pyrrolidone; IV) prolonged release coating layer with ethylcellulose and polyethylene glycol. Use of said composition and method of treating neurodegenerative disease or damage of nervous system are also described.
EFFECT: invention provides intensified effect on above diseases.
16 cl, 9 dwg, 17 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
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