METHOD FOR PREDICTING COURSE OF ACUTE ISCHEMIC STROKE Russian patent published in 2017 - IPC A61B5/00 

FIELD: medicine.

SUBSTANCE: HRV is performed twice during a year and the following time and spectral indices are evaluated: SDNN, SDANN (ms), RMSSD (ms), pNN50, HF (ms²), VLF (ms²). Change of each index is calculated in per cent and measurements are evaluated in points. "0" points is given in case of reduction of indices SDNN, SDANN, RMSSD, pNN50, HF and increase of index VLF by less than 10% of the initial level. If change of index is from 10 to 20% - "1 point", if change of index is from 20 to 30% - "2 points", if change of index is from 30 to 40% - "3 points", if change of index is from 40 to 50% - "4 points", if change of index exceeds 50% - "5 points". If day indices of heart rate variability prevail over night ones in first and second examinations, "1 point" is additionally given for each examination. The sum of all values of points (∑BP) is calculated by original formula. Probability of unfavourable outcome in case of development of acute ischemic stroke is estimated by the following criteria: low - ∑BP - from 0 to 9 points; medium - ∑BP - from 10 to 20 points; high - ∑BP - more than 20 points.

EFFECT: method makes it possible to realise prediction of disease course and form groups of risk of AIS development in patients with presence of cardiovascular pathology, detected before development of ischemic stroke.

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