FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of pharmaceutics. Described is dispersible in water acetylcysteine tablet, which contains from 100 to 600 mg of said substance and auxiliary components, taken in ratio 1:1 to the total weight from 200 to 1200 mg. Active and auxiliary substances are used in the following weight ratio, %: acetylcysteine - 50.0; microcrystalline cellulose - 34.1; lactose monohydrate - 5.0; crospovidone - 5.0; povidone - 25-2.0; lemon flavour - 1.0; sodium saccharinate - 0.825; aspartame - 0.675; citric acid monohydrate - 0.325; colloidal silicon dioxide - 0.75; magnesium stearate - 0.75. Tablet is capable of dispersing in water at temperature 15-25°C within 3 minutes with formation of dispersion, consisting of particles with size smaller than 710 mcm.
EFFECT: obtained tablet possesses high stability and physical preservation, good mechanical properties in combination with fast disintegration in water solutions.
2 cl, 3 ex, 4 tbl
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