FIELD: pharmacology.
SUBSTANCE: invention describes a pharmaceutical composition in the form of a dispersible pill comprising desloratadine and a method for its manufacture. A water-dispersible desloratadine pill is prepared by compressing the active ingredient in an amount of 2.5 or 5.0 mg with processing aids and pharmaceutically acceptable excipients and is capable of dispersing in water for 3 minutes to form a dispersion consisting of particles smaller than 710 mcm. The obtained pill possesses high stability and physical preservation, good mechanical properties in combination with fast disintegration in water solutions.
EFFECT: experimentally selected composition allows for high processability of the dispersible pill manufacturing process.
2 ex, 2 tbl
