FIELD: medicine.
SUBSTANCE: lens includes a non-through depots, filled with drug substance. Lens diameter is 14.3-15 mm. The lens edge has a 1 mm wide chamfer with radius 1 mm greater than the inner lens radius. Depots are arranged as a grid on the outer lens surface except for the pupillary area, 5.0-8.0 mm in diameter or in annular recesses on the inner peripheral surface of the lens. Depots have the form of a hemisphere with microgrooves on the inner surface. The outer lens surface contains 50-750 depots. The inner lens surface contains 50-300 depotsm, from 1 to 3 in each 1.0 mm wide annular recess. A hemispheric depot has a diameter of 100 microns and depth of 30-40 microns. The microgrooves are located in a quantity of 5-100 and have a length of 5-10 mm and a width of 500 nm - 4 microns.
EFFECT: possibility of therapeutic MCL saturation with lipophilic and macromolecular materials with different optical density, increased range of applied medical means, increased accuracy of drug dosing due to the maximum approach of depots with drugs to the diseased tissue, expanding the indications for lens application.
5 cl, 2 dwg, 2 ex
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Authors
Dates
2017-03-02—Published
2016-01-27—Filed