FIELD: medicine.
SUBSTANCE: silicone-hydrogel soft contact lens (SCL) saturated with 0.05% Cyclosporin A (CyaA) is used. Ciclosporin A is used in the form of an emulsion and used to saturade an SCL with non-blind depots in the form of a hemisphere with microscopic incisions on the inner surface located on the external or internal surface of the lens. Drug substance saturation is carried out under vacuum conditions at a pressure of 2600 Pa, until the depots are fully filled up under the control of an electron scanning microscope. The lens is used around the clock for 7-14 days against the background of installations of a non-conservative douche in the conjunctival cavity up to 6 times a day. The course of treatment is repeated after re-saturation of the same SCL.
EFFECT: method provides a prolonged, persistent anti-inflammatory and immunosuppressive effect with accelerated epithelialization of corneal defects in the absence of side effects of Ciclosporin A.
4 cl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SILICONE HYDROGEL THERAPEUTIC SOFT CONTACT LENS | 2016 |
|
RU2612121C1 |
| METHOD OF TREATING PERIPHERAL ULCERATIVE KERATITIS ACCOMPANYING SJOGREN'S SYNDROME ASSOCIATED WITH RHEUMATOID ARTHRITIS | 2015 |
|
RU2585611C1 |
| METHOD OF TREATING INFLAMMATIONS OF ANTERIOR EYE SEGMENT | 2013 |
|
RU2513597C1 |
| METHOD OF PREDICTION SEVERE FORM OF DRY EYE SYNDROME IN SJÖGREN SYNDROME ASSOCIATED WITH RHEUMATOID ARTHRITIS | 2018 |
|
RU2679799C1 |
| METHOD FOR THE TREATMENT OF PERSISTENT EPITHELIAL CORNEAL DEFECT | 2022 |
|
RU2792394C1 |
| MEANS FOR TREATING THE CASES OF DRY EYE SYNDROME | 2004 |
|
RU2285511C2 |
| METHOD OF EARLY CONSERVATIVE TREATMENT OF MILD AND MODERATE CORNEAL BURNS | 2023 |
|
RU2811887C1 |
| METHOD OF TREATING RECURRENT EROSION OF CORNEAS OF VARIOUS ORIGINS | 2019 |
|
RU2716429C1 |
| METHOD FOR SURGICAL TREATMENT OF CORNEAL DEFECTS OF VARIOUS ORIGINS | 2022 |
|
RU2782129C1 |
| METHOD OF TREATMENT OF INSUFFICIENCY OF BASAL SECRETION OF TEAR | 2006 |
|
RU2340315C2 |
