FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, specifically to immunology, and can be used for producing vaccine for treating cancer in mammal. Cancer vaccine contains cancer cells expressing one or more antigens and excipients, wherein above antigen is expressed by cancer cells with increased level of p38 and where above cancer cells are prepared by contacting of above cancer cells with Mycobacterium w. Group of inventions also relates to method of treating cancer in mammals, involving administering therapeutically effective amount of above cancer vaccine.
EFFECT: use of this group of inventions allows to induce both humoral and cell-mediated immune response against homologous and heterologous tumor cells.
12 cl, 4 ex, 1 tbl, 10 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| CANCER ANTIGEN | 2012 |
|
RU2607379C2 |
| ANTICANCER COMPOSITION CONTAINING A RECOMBINANT ADENOVIRUS EXPRESSING A DESTRUCTIVE FACTOR FOR AN EXTRACELLULAR MATRIX | 2017 |
|
RU2742726C2 |
| COMPOSITIONS CAUSING SPECIFIC RESPONSE OF CYTOTOXIC T-LYMPHOCYTES, INCLUDING LYMPH-ABLATIVE COMPOUND AND MOLECULE WHICH CONTAINS ANTIGEN SEQUENCES AND IS TARGETED AT SPECIALISED ANTIGEN-PRESENTING CELLS | 2007 |
|
RU2448729C2 |
| COMBINATION OF RECOMBINANT MICROBACTERIUM AND BIOLOGICALLY ACTIVE AGENT AS VACCINE | 2005 |
|
RU2495677C2 |
| INDIVIDUALIZED ANTI-TUMOR VACCINES | 2012 |
|
RU2779946C2 |
| FOXM1 PEPTIDE AND MEDICINAL AGENT CONTAINING SAID PEPTIDE | 2008 |
|
RU2487886C2 |
| INDIVIDUALISED VACCINES FOR CANCER | 2012 |
|
RU2670745C9 |
| CDCA1 PEPTIDE AND PHARMACEUTICAL DRUG CONTAINING IT | 2008 |
|
RU2486195C2 |
| METHOD OF ANTITUMOUR IMMUNOTHERAPY | 2012 |
|
RU2530523C2 |
| TUMOUR VACCINE CONTAINING ALLOGENIC OR XENOGENIC TUMOUR CELLS | 2007 |
|
RU2456997C2 |
