FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, specifically to immunology, and can be used for producing vaccine for treating cancer in mammal. Cancer vaccine contains cancer cells expressing one or more antigens and excipients, wherein above antigen is expressed by cancer cells with increased level of p38 and where above cancer cells are prepared by contacting of above cancer cells with Mycobacterium w. Group of inventions also relates to method of treating cancer in mammals, involving administering therapeutically effective amount of above cancer vaccine.
EFFECT: use of this group of inventions allows to induce both humoral and cell-mediated immune response against homologous and heterologous tumor cells.
12 cl, 4 ex, 1 tbl, 10 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| CANCER ANTIGEN | 2012 |
|
RU2607379C2 |
| COMBINATION OF RECOMBINANT MICROBACTERIUM AND BIOLOGICALLY ACTIVE AGENT AS VACCINE | 2005 |
|
RU2495677C2 |
| ANTICANCER COMPOSITION CONTAINING A RECOMBINANT ADENOVIRUS EXPRESSING A DESTRUCTIVE FACTOR FOR AN EXTRACELLULAR MATRIX | 2017 |
|
RU2742726C2 |
| FOXM1 PEPTIDE AND MEDICINAL AGENT CONTAINING SAID PEPTIDE | 2008 |
|
RU2487886C2 |
| COMPOSITIONS CAUSING SPECIFIC RESPONSE OF CYTOTOXIC T-LYMPHOCYTES, INCLUDING LYMPH-ABLATIVE COMPOUND AND MOLECULE WHICH CONTAINS ANTIGEN SEQUENCES AND IS TARGETED AT SPECIALISED ANTIGEN-PRESENTING CELLS | 2007 |
|
RU2448729C2 |
| INDIVIDUALIZED ANTI-TUMOR VACCINES | 2012 |
|
RU2779946C2 |
| CDCA1 PEPTIDE AND PHARMACEUTICAL DRUG CONTAINING IT | 2008 |
|
RU2486195C2 |
| METHOD OF ANTITUMOUR IMMUNOTHERAPY | 2012 |
|
RU2530523C2 |
| THERAPEUTIC CANCER VACCINE BASED ON STRESS PROTEINS AS IMMUNOGENS | 2014 |
|
RU2694761C2 |
| TUMOUR VACCINE CONTAINING ALLOGENIC OR XENOGENIC TUMOUR CELLS | 2007 |
|
RU2456997C2 |
