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2 617 042

(13)

(51)

IPC

A61K31/245(2006-01-01)

A61K38/24(2006-01-01)

A61P15/08(2006-01-01)

(21) (22)

Application

2016124629, 2016-06-21

(24)

Start date

2016-06-21

(22)

Actual filing date

2016-06-21

(45)

Published

2017-04-19

(72)

Inventor

Kosovskij Gleb YurevichPopov Dmitrij VladimirovichBrigida Artem Vladimirovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Eksperimentalnoj Embriologii I Reproduktivnykh Biotekhnologij" Tseerb)

METHOD OF INDUCTION OF SUPEROVULATION IN COWS-DONORS EMBRYONES WITH PROLONGATION OF ACTIVITY OF HYPOPHYSICAL GONADOTROPINS Russian patent published in 2017 - IPC A61K31/245 A61K38/24 A61P15/08

Abstract RU 2617042 C2

FIELD: veterinary medicine.

SUBSTANCE: method comprises a single administration of donor cows in the luteal phase of the sexual cycle of the drug, containing pituitary gonadotropins Follicle stimulating hormone (FSH) and luteinizing hormone (LH), combined with prolongatory. After 48 hours, prostaglandin F2α is injected. Additionally, 0.25-1% novocaine solution in an amount of 3-15 ml is injected. This novocaine solution is injected simultaneously in combination with a preparation containing hypophyseal gonadotropins FSH and LH is combined with prolongatory, wherein prolongator is used as a biodegradable polymer is polyethylene glycol (PEG) with a mass of 6,000 to 70,000 Da in an amount of 0.5-7 g. The preparation, containing hypophyseal gonadotropins FSH and LH, is injeted in a total dose recommended by instructions of this drug to induce superovulation.

EFFECT: method allows to increase the number of quality embryos obtained from donor cows as a result of induction of superovulation.

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RU 2 617 042 C2

Authors

Kosovskij Gleb Yurevich

Popov Dmitrij Vladimirovich

Brigida Artem Vladimirovich

Dates

2017-04-19—Published

2016-06-21—Filed