FIELD: medicine.
SUBSTANCE: rats are preliminarily subjected to continuous exposure to cold at a temperature of +2°C for 4 weeks with a standard diet and light. Then a 45-minute coronary occlusion is performed followed by a 2-hour reperfusion.
EFFECT: method allows to conduct research aimed at studying of the receptor and molecular mechanisms of the infarct-limiting effect of adaptation to chronic continuous cold exposure.
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