5-ARYL-SUSTITUTED 4-(5-NITROFURAN-2-YL)PYRIMIDINE, WITH WIDE SPECTRUM OF ANTIBACTERIAL ACTIVITY, METHOD FOR ITS PRODUCTION AND INTERMEDIATE COMPOUND WITH WIDE SPECTRUM OF ANTIBACTERIAL ACTIVITY Russian patent published in 2017 - IPC C07D405/04 A61K31/506 A61P31/04 

Abstract RU 2626647 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to 5-aryl-substituted 4-(5-nitrofuran-2-yl)pyrimidines , as well as a process for their preparation using intermediate compound. The resulting compounds (Ia-d and II) can be used to treat patients with diseases of the genitourinary system caused by Staphylococcus aureus or gonococci.

EFFECT: highly effective method for preparation of these compounds, which have a broad spectrum of antibacterial activity, is proposed.

3 cl, 2 tbl, 4 ex

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RU 2 626 647 C1

Authors

Verbitskij Egor Vladimirovich

Baskakova Svetlana Anatolevna

Gerasimova Natalya Avenirovna

Evstigneeva Natalya Petrovna

Amineva Polina Gennadevna

Zilberberg Natalya Vladimirovna

Kungurov Nikolaj Vasilevich

Rusinov Gennadij Leonidovich

Chupakhin Oleg Nikolaevich

Charushin Valerij Nikolaevich

Dates

2017-07-31Published

2016-08-19Filed