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IPC

C07D487/04(2006-01-01)

A61K31/395(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2020141934, 2020-12-18

(24)

Start date

2020-12-18

(22)

Actual filing date

2020-12-18

(45)

Published

2021-09-03

(72)

Inventor

Charushin Valerij NikolaevichKorotina Anna VladimirovnaTolshchina Svetlana GennadevnaIshmetova Rashida IrshotovnaGerasimova Natalya AvenirovnaEvstigneeva Natalya PetrovnaZilberberg Natalya VladimirovnaKungurov Nikolaj VasilevichRusinov Gennadij LeonidovichChupakhin Oleg Nikolaevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Organicheskogo Sinteza Im. I.Ya. Postovskogo Uralskogo Otdeleniya Rossijskoj Akademii NaukGosudarstvennoe Byudzhetnoe Uchrezhdenie Sverdlovskoj Oblasti Nauchno-Issledovatelskij Institut Dermatovenerologii I Immunopatologii"

4-ISOPROPYL-6-R-IMIDAZO[1,2-B][1,2,4,5]TETRAZIN-3(4H)- ES WITH ANTIBACTERIAL ACTIVITY AGAINST NEISSERIA GONORRHOEAE Russian patent published in 2021 - IPC C07D487/04 A61K31/395 A61P31/04

Abstract RU 2754554 C1

FIELD: antibacterial agents.

SUBSTANCE: invention relates to 4-isopropyl-6-R-imidazo[1,2-b][1,2,4,5]tetrazin-3-ones, which are antibacterial agents active against the gram-negative bacteria Neisseria gonorrhoeae, which are compounds of the formula 1, in which R is H (1a), isopropylthio (1b), benzylthio (1c).

EFFECT: new 4-isopropyl-6-R-imidazo[1,2-b][1,2,4,5]tetrazin-3-es have been obtained, which have antibacterial activity against Neisseria gonorrhoeae and which can be used to create medicines for the treatment diseases caused by them.

1 cl, 2 tbl, 3 ex

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RU 2 754 554 C1

Authors

Charushin Valerij Nikolaevich

Korotina Anna Vladimirovna

Tolshchina Svetlana Gennadevna

Ishmetova Rashida Irshotovna

Gerasimova Natalya Avenirovna

Evstigneeva Natalya Petrovna

Zilberberg Natalya Vladimirovna

Kungurov Nikolaj Vasilevich

Rusinov Gennadij Leonidovich

Chupakhin Oleg Nikolaevich

Dates

2021-09-03—Published

2020-12-18—Filed