METHOD FOR ASSESSMENT OF CHRONIC GENERALIZED PERIODONTITIS TREATMENT EFFECTIVENESS Russian patent published in 2017 - IPC A61B5/00 G01N33/92 

FIELD: medicine.

SUBSTANCE: invention relates to the study of the physical and chemical properties of a biological fluid, and can be used in therapeutic dentistry to evaluate the effectiveness of treatment of chronic generalized periodontitis (CHG) in patients with metabolic syndrome (MS). The method includes a biochemical analysis of oral fluid before and after treatment in patients with diagnosed chronic generalized periodontitis and diagnosed metabolic syndrome, using a spectrophotometric assay, the lipid profile of the oral fluid is determined, namely the concentration of triglycerides (TG), total cholesterol (TC), low density lipoprotein (LDL) and high-density lipoprotein (HDL). When TG concentration changes from 0.04±0.01 mmol/l to 0.01±0.001 mmol/l, TC changes from 0.08±0.02 mmol/l to 0.04±0.02 mmol/l, LDL changes from 0.04±0.001 mmol/l to 0.01±0.001 mmol/l, HDL changes from 0.08±0.01 mmol/l to 0.12±0.01 mmol/l, treatment is evaluated as effective. Significant changes in the lipid profile in the oral fluid of patients with generalized periodontitis (P<0.01) suggest that for the evaluation of the HCV treatment effectiveness, saliva study is indicative and can be recommended for use under the conditions of periodontics department.

EFFECT: improved assessment accuracy.

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