METHOD OF TRANSDERMAL DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES Russian patent published in 2017 - IPC A61N7/00 A61K31/37 A61K33/06 A61P43/00 A61M35/00 B82Y5/00 

Abstract RU 2633928 C1

FIELD: medicine.

SUBSTANCE: for the transdermal delivery of biologically active substances (BAS), the application of containers with immobilized BAS to the surface of the skin is carried out, followed by transportation through the appendages of the skin. Porous calcium carbonate particles in a crystallographic modification of a vaterite with a size of less than 1,5 mcm are used as the containers. Transportation is carried out by exposing to ultrasound with an intensity of 0.1-1 W/cm2 with a duration of 1-4 minutes.

EFFECT: effective filling of the hair follicles with particles while accelerating the procedure of introduction and providing the possibility to control the release duration of biologically active substances.

4 cl, 2 tbl, 47 dwg, 15 ex

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RU 2 633 928 C1

Authors

Svenskaya Yuliya Igorevna

Genina Elina Alekseevna

Guslyakova Olga Igorevna

Parakhonskij Bogdan Vladislavovich

Gorin Dmitrij Aleksandrovich

Sukhorukov Gleb Borisovich

Tuchin Valerij Viktorovich

Zajtsev Sergej Mikhajlovich

Bashkatov Aleksej Nikolaevich

Talnikova Ekaterina Evgenevna

Bucharskaya Alla Borisovna

Terentyuk Georgij Sergeevich

Utts Sergej Rudolfovich

Dates

2017-10-19Published

2016-08-24Filed