FIELD: pharmacology.
SUBSTANCE: invention is a pharmaceutical composition comprising vortioxetine and donepezil together with a pharmaceutically acceptable excipient, the composition is for treatment of a disease selected from cognitive dysfunction, dementia in Alzheimer's disease, dementia of vascular genesis, dementia in Pick's disease, dementia in Creutzfeldt-Jakob disease, dementia in Huntington's disease, dementia in Parkinson's disease, dementia in the human immunodeficiency virus, dementia in persons abusing alcohol or medication, moderate cognitive impairment, cognitive dysfunction associated with depression, and cognitive dysfunction associated with schizophrenia.
EFFECT: invention provides a synergistic increase in the extracellular level of acetylcholine in the brain.
12 cl, 5 ex, 1 tbl, 6 dwg
