METHOD FOR EXTENSION OF DRUG ACTION DURING INTRALACUNAR INTRODUCTION INTO TONSILS Russian patent published in 2017 - IPC A61K31/00 A61K47/10 A61P11/04 

FIELD: medicine.

SUBSTANCE: invention is intended for palatine tonsils sanation during local treatment of chronic tonsillitis in persons with contradictions to administration of drugs to the palatine tonsil by phonophoresis. In the local treatment of chronic tonsillitis, a glycerol-containing drug is injected into the open mouths of lacunae treated with physiological solution, after closing of the lacunae mouths, an aseptic adhesive gum balm is applied to them. As a glycerol-containing drug, Candide solution is used. Also, a mixture of levomycetin, glycerin and physiological sodium chloride solution is used for preparation of which 4.0 ml of eyedrops "Levomycetin 0.25%", 0.2 ml of glycerol for external and topical administration and 0.8 ml of 0.9% physiological solution of sodium chloride are mixed, or these substances are mixed in other amounts, multiple thereof.

EFFECT: long drug depot in the palatine tonsils lacunae, which ensures a prolonged drug contact with the epithelial surface of the tonsil mucosa in the lacunae.

3 cl, 2 ex