FIELD: veterinary medicine.
SUBSTANCE: mehod includes obtaining of supramolecular antihelmintic agent and differs by niclosamide injection into propylene glycol in the ratio of 6:1, solvent temperature to 120-130°C and mixing thoroughly until complete dissolution of niclosamide, then polyvinylpolypyrrolidone (PVP) is added to the niclosamide solution in the ratio 14:1 with careful PVP stirring in the niclosamide solution until complete dilution, wheat bran in a ratio of 6:1 is added as a filler, and then ground chalk, salt and feed molasses are introduced at a ratio of 1:50:200:2, carefully stirred, the resulting mixture is subjected to pelletizing, pellet diameter is 5 mm.
EFFECT: method allows to achieve savings of substances for drug preparation, lower therapeutic dose due to the drug bioavailability, reduce the toxicity of feed, environmental pollution, reduce drug cost and economize water birds treatment by the group method.
3 ex
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Authors
Dates
2017-12-04—Published
2016-11-01—Filed