FIELD: pharmacology.
SUBSTANCE: invention relates to compounds of formula (Ib) in which Q is mono- or poly-M1 a substituted pyridyl, thienyl, furanyl or isothiazolyl; Y is hydrogen or cyclopropyl; W is oxygen or sulfur; L2 is -C(R21, R22)-; L3 is -C(R31, R32) - or a direct link; R21, R22 each independently is hydrogen, fluorine or, if necessary, mono- or poly-M2-substituted (C1-C4)-alkyl, (C2-C4)-alkenyl, (C2-C4)-alkynyl, (C1-C4)-haloalkyl, (C1-C6)-alkoxy, (C2-C4)-alkenyloxy, (C3-C4)-alkynyloxy, (C3-C4)-cycloalkyl-(C1-C4)-alkyl or (C3-C6)-cycloalkyl; R31, R32 each independently is hydrogen or (C1-C4)-alkyl; M2 each independently are chlorine, fluorine, formyl, cyano, nitro, (C1-C4)-alkyl, (C1-C4)-haloalkyl, (C1-C4)-alkoxy, (C1-C4)-haloalkoxy, (C1-C4)-alkylthio, (C1-C4)-haloalkylthio, (C1-C4)-alkylsulfonyl, (C1-C4)-haloalkylsulfonyl, (C1-C4)-alkylsulfanyl, (C1-C4)-haloalkylsulfanyl, (C1-C4)-alkylcarbonyl, (C1-C4)-haloalkylcarbonyl or (C3-C6)-cycloalkyl; M1 and M3 independently are halogen, cyano, nitro, OH, (C1-C10)-alkyl, (C1-C10)-haloalkyl, (C1-C10)-alkoxy, (C1-C10)-haloalkoxy, (C1-C10)-alkylthio, (C1-C10)-haloalkylthio, (C1-C10)-alkylsulfonyl, (C1-C10)-haloalkylsulfonyl, (C1-C10)-alkylsulfanyl, (C1-C10)-haloalkylsulfanyl, optionally substituted by halogen (3-14-membered cyclic group)-O-; n is an integer from 0 to 4; and to their use as medicines for controlling endoparasites in animals or humans.
EFFECT: increased efficiency.
16 cl, 29 tbl
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Authors
Dates
2017-12-18—Published
2012-11-23—Filed