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2 639 147

(13)

(51)

IPC

C07J1/00(2006-01-01)

C07J5/00(2006-01-01)

C07J21/00(2006-01-01)

A61K31/56(2006-01-01)

(21) (22)

Application

2017118065, 2017-05-24

(24)

Start date

2017-05-24

(22)

Actual filing date

2017-05-24

(45)

Published

2017-12-20

(72)

Inventor

Andryushina Valentina AleksandrovnaStytsenko Tatyana SemenovnaKarpova Natalya ViktorovnaDzhavakhiya Vakhtang VitalevichSkryabin Konstantin Georgievich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennostyu

METHOD OF PRODUCING 17,17-ETHYLENEDIOXY-ANDROSTA-1,4-DIEN-3-ONE Russian patent published in 2017 - IPC C07J1/00 C07J5/00 C07J21/00 A61K31/56

Abstract RU 2639147 C1

FIELD: chemistry.

SUBSTANCE: improved method of producing a known compound of the androstane series, 17,17-ethylenedioxy-androsta-1,4-dien-3-one is proposed. The process is carried out by reacting androsta-1,4-diene-3,17-dione with ethylene glycol in a heterogeneous medium in the presence of trialkyl orthoformate and arylsulfonic acid, followed by isolation of the desired product by filtration directly from the previously neutralized reaction mass.

EFFECT: new improved method is developed.

2 cl, 1 tbl

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RU 2 639 147 C1

Authors

Andryushina Valentina Aleksandrovna

Stytsenko Tatyana Semenovna

Karpova Natalya Viktorovna

Dzhavakhiya Vakhtang Vitalevich

Skryabin Konstantin Georgievich

Dates

2017-12-20—Published

2017-05-24—Filed