FIELD: pharmacology.
SUBSTANCE: group of inventions refers to a pharmaceutical composition for induction of apoptosis in a cell with a mutated KRAS containing an effective amount of a drug that suppresses GST-π; and an effective amount of a drug that suppresses autophagy. A method for apoptosis induction in a cell with a mutated KRAS, in particular in a cancer cell with a KRAS mutation, is also claimed.
EFFECT: increased efficiency of apoptosis in the cell.
8 cl, 18 dwg, 6 ex
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| THERAPEUTIC COMBINATIONS CONTAINING RAF INHIBITOR AND ERK INHIBITOR |
2017 |
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2008 |
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2010 |
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