AGENT INDUCING CELL DEATH FOR CELLS HAVING BRAF GENE MUTATIONS, AGENT SUPPRESSING GROWTH OF SUCH CELLS, AND PHARMACEUTICAL COMPOSITION FOR THE THERAPY OF DISEASES CAUSED BY GROWTH DEFECT OF SUCH CELLS Russian patent published in 2021 - IPC A61K45/06 A61K31/713 A61K48/00 A61P35/00 A61P43/00 

Abstract RU 2760835 C2

FIELD: medicine.

SUBSTANCE: method for inducing cell death of a cell having BRAF gene mutation, a method for suppressing cell growth of a cell having BRAF gene mutation, the application of a drug suppressing GST-π production for the treatment of cancer caused by cell growth defect, and the application of a drug suppressing GST-π production and BRAF inhibitor for the treatment of cancer caused by growth defect of a cell having BRAF gene mutation are proposed. A method for screening a drug for inducing cell death of a cell having BRAF gene mutation, and a method for screening a drug for suppressing cell growth of a cell having BRAF gene mutation are proposed.

EFFECT: proposed group of inventions provides for inducing cell death and suppressing cell growth of a cell having BRAF gene mutation.

10 cl, 6 dwg, 3 ex

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RU 2 760 835 C2

Authors

Nishita Hiroki

Nisita Khiroki

Dates

2021-11-30Published

2016-04-15Filed