PEPTIDES SUPPRESSING RESPIRATORY VIRUSE INFECTIONS, THEIR APPLICATION AND METHODS FOR OBTAINING Russian patent published in 2017 - IPC C07K14/47 C12N15/11 C12N5/10 C12N15/63 A61K38/17 A61P31/12 

FIELD: pharmacology.

SUBSTANCE: inventions relate to a peptide synthesized chemically or genetically engineered, compositions comprising such a peptide, DNA coding a polypeptide, vector incorporating such a DNA, a host cell for expression of the peptide, a peptide screening Kit, capable of suppressing a respiratory virus infection and a method for screening of a peptide capable of suppressing a respiratory virus infection. The presented peptide contains 5 or more essential amino acids, 2 or more of these essential amino acids are located in the N-terminal or C-terminal region, and the N-terminal region contains a sequence of no more than 10 amino acids from the peptide N-terminal amino acid and the C-terminal region contains a sequence of no more than 10 amino acids from the peptide C-terminal amino acid, while the peptide consists of a sequence of amino acids, at least 90% identical to SEQ ID NO: 10.

EFFECT: possibility of application of inventions to block infections of respiratory viruses such as influenza viruses or coronaviruses in the target cells for prevention and treatment of these infections.

23 cl, 10 dwg, 3 tbl, 1 ex