FIELD: chemistry.
SUBSTANCE: invention relates to intermediate compounds of the formula I , where R12 is selected from C1-C8-alkyl with a straight and branched chain; each R10 is independently selected from hydrogen, R12 and -OR12; each R8 and R9 are independently selected from C1-C8-alkyl with a straight and branched chain; r is 0; G is oxygen; Z1 is C1-C5-alkyl with a straight or branched chain; Ar is a 1.2-, 1.3 - or 1.4-phenylene; W is selected from -O - and -S-; and Y is a (C1-C6)alkylene group with a straight or branched chain, and also to the methods of synthesis and purification of calicheamicin derivatives.
EFFECT: improving the properties of compounds.
24 cl, 8 ex
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Authors
Dates
2017-12-27—Published
2014-10-28—Filed