METHOD FOR INCREASE OF ORGANISM RESISTANCE TO COMBINED TOXIC ACTION OF NANOPARTICLES OF COPPER, ZINC AND LEAD OXIDES Russian patent published in 2018 - IPC A61K31/198 A61K31/202 A61K35/60 A61K31/732 A61P39/00 

Abstract RU 2642674 C1

FIELD: medicine.

SUBSTANCE: method for reduction of the adverse effects of combined effects of copper (CuO), zinc (ZnO) and lead (PbO) oxides nanoparticles on organism in risk groups covering individuals exposed to such effects under production conditions. Method includes prescription of a complex of biologically active drugs: glutaminic acid, glycine, N-acetylcysteine, pectin enterosorbent, fish oil preparation rich in unesterified omega-3 fatty acids, Vitamins A, C, D3, E, selenium, iron and iodized preparations. This complex is taken by repeated courses 1-2 times a year for 4-6 weeks daily at doses providing daily intake of 300 mg of glycine, 600 mg of cysteine, 4 g of glutaminic acid, 25 ml of fish oil with 12-15% content of polyunsaturated omega-3 fatty acids, 4-5 grams of pectin, as well as selenium, iron, iodine and these vitamins in doses that provide the normal physiological needs of the organism.

EFFECT: reduction of all three metals in the blood, improved elimination function of the liver and kidneys, reduced integral signs of chronic intoxication, including signs of neurotoxicity, and genotoxic combined action of copper, zinc and lead oxides nanoparticles on the body.

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Authors

Minigalieva Ilzira Amirovna

Katsnelson Boris Aleksandrovich

Privalova Larisa Ivanovna

Gurvich Vladimir Borisovich

Sutunkova Marina Petrovna

Shur Vladimir Yakovlevich

Shishkina Ekaterina Vladimirovna

Valamina Irina Evgenevna

Zubarev Ilya Vladimirovich

Makeev Oleg Germanovich

Meshcheryakova Ekaterina Yurevna

Dates

2018-01-25Published

2017-02-21Filed