MEDICAL AND COSMETIC MEANS FOR EXTERNAL APPLICATION Russian patent published in 2018 - IPC A61K33/42 A61K31/66 A61K47/00 A61K8/24 A61K8/55 

FIELD: pharmacology.

SUBSTANCE: preparation contains a mixture of disodium pyrophosphate and tetrakali pyrophosphate in a weight ratio of 1:1 in an amount of 0.05-3.0 wt %, contains potassium sodium salt of hydroxyethylidenebisphosphonic acid or 1-hydroxy-3-dimethylamino-propylidenebisphosphonic acid in an amount of 0.005-2.0 wt % as the bisphosphonate, lipids in an amount up to 35.0 wt %, emulsifiers in an amount of 0.1-15.0 wt %, structurants in an amount up to 10.0 wt %, flavouring in an amount up to 3.0 wt %, dyes in an amount up to 0.1 wt %, preservatives in an amount of 0.01-1.0 wt %, biologically active and drug additives in an amount of 1.0-10.0 wt % and water in an amount up to 100%. As biologically active and drug additives, the agent contains glycerol, lecithin, glycine, camphor, menthol, carbamide, sorbitol, succinic acid, citric acid, vitamins A, E, collagen, glucosamine hydrochloride, betaine natural, essential oils of rosemary, eucalyptus, Siberian fir, water-alcohol extracts of St. John's wort, juniper, rhodiola rosea, water extracts of green tea, sage, carbonic extract of hot pepper, aloe vera gel.

EFFECT: decreased intensity of crystallization of poorly soluble calcium salts in skin cells, thus eliminating salts deposition in the basal layer of the epidermis.

2 cl, 1 dwg, 4 ex