FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically to a process for preparation of tricyclic indole compounds of formula Z. Method comprises cyclizing a compound having formula Y by introducing a zinc halide in a suitable solvent into a solution of said compound having formula Y, said introduction comprising a first addition and a second addition performed at least 6 hours after said first addition.
, .
EFFECT: process provides improved conversion, which increases yield and avoids significant treatment of the cyclized product.
8 cl, 1 tbl, 1 ex
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Authors
Dates
2018-03-21—Published
2013-11-29—Filed