METHOD FOR PREPARATION OF BENZOXAZEPINE COMPOUNDS Russian patent published in 2018 - IPC C07D498/04 A61K31/4162 A61K31/4196 

Abstract RU 2649976 C2

FIELD: chemistry.

SUBSTANCE: invention relates to processes for preparation of a compound of formula (I): . Method for preparing a compound GDC-0032, which is an inhibitor of PI3K, which can be used to prepare a compound of formula I on an industrial scale, where a special selection of reactions was carried out, the combination of which led to a reduction in the mass of reagents used while simultaneously eliminating harmful and dangerous reagents.

EFFECT: method for preparing compound GDC-0032, which is an inhibitor of PI3K, has been developed.

8 cl, 37 ex

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RU 2 649 976 C2

Authors

Anzhelo Remi

Bodri Danial R.

Karrera Dajan E.

Malkhotra Sushant

Remarchuk Trevis

St-Zhan Frederik

Dates

2018-04-06Published

2014-03-12Filed