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2 650 044

(13)

(51)

IPC

G09B23/28(2006-01-01)

A61K31/13(2006-01-01)

A61P1/14(2006-01-01)

A61P1/16(2006-01-01)

(21) (22)

Application

2017108696, 2017-03-16

(24)

Start date

2017-03-16

(22)

Actual filing date

2017-03-16

(45)

Published

2018-04-06

(72)

Inventor

Silverstova Svetlana YurevnaLychkova Alla EduardovnaPetrakov Aleksandr VasilevichPuzikov Aleksandr Mikhajlovich

(73)

Holder

Gosudarstvennoe Byudzhetnoe Uchrezhdenie Zdravookhraneniya Goroda Moskvy Moskovskij Klinicheskij Nauchno-Prakticheskij Tsentr Departamenta Zdravookhraneniya Goroda Moskvy

CORRECTION OF ACTIVITY OF INTESTINAL MICROBIOTA IN FATTY LIVER DISEASE IN AN EXPERIMENT Russian patent published in 2018 - IPC G09B23/28 A61K31/13 A61P1/14 A61P1/16

Abstract RU 2650044 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to methods for correcting the activity of intestinal microbiota in fatty liver disease in an experiment. To do this, modeling fatty liver dystrophy in rats by adding a protein-fat mixture to the standard diet in a ratio of 70:30 in an amount of 12–15 g for 3–3.5 months. Method includes daily, intraperitoneal administration during this time period of serotonin in a dose of 50–100 mcg/kg.

EFFECT: method provides effective correction of the intestinal microbiota in fatty liver disease.

1 cl, 4 ex

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RU 2 650 044 C1

Authors

Silverstova Svetlana Yurevna

Lychkova Alla Eduardovna

Petrakov Aleksandr Vasilevich

Puzikov Aleksandr Mikhajlovich

Dates

2018-04-06—Published

2017-03-16—Filed