FUSED PYRROLEDICARBOXAMIDES AND THEIR USE AS PHARMACEUTICALS Russian patent published in 2018 - IPC C07D471/04 C07D498/04 C07D513/04 A61K31/437 A61K31/5365 A61K31/5383 A61P9/06 A61P11/00 

Abstract RU 2650111 C2

FIELD: medicine.

SUBSTANCE: invention relates to condensed pyrrolidicarboxamides of formula I (I).

EFFECT: technical result - new compounds of formula I are obtained which are inhibitors of acid-sensitive potassium channels TASK-1 and are suitable for the treatment of diseases mediated by TASK-1 channels, for example, such as arrhythmias, in particular atrial arrhythmias, such as atrial fibrillation or atrial flutter, and respiratory disorders, in particular sleep-related respiratory disorders, such as sleep apnea.

15 cl, 18 tbl

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RU 2 650 111 C2

Authors

Biali Loran

Lorents Katrin

Virt Klaus

Shtajnmejer Klaus

Khessler Gerkhard

Dates

2018-04-09Published

2013-02-01Filed