FIELD: medicine.
SUBSTANCE: invention relates to medicine and a method of treating hemorrhagic shock or massive blood loss in mammals, which comprises administering tranexamic acid to a mammal in the amount between 0.005 and 0.5 g/kg of the body weight in combination with recombinant full-size SERPING1 or its serpin domain in the amount of 10 to 900 IU/kg of the body weight.
EFFECT: invention provides a significant reduction of mortality caused by hemorrhagic shock or massive blood loss.
6 cl, 8 ex, 10 dwg, 4 tbl
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Authors
Dates
2018-04-23—Published
2015-09-18—Filed