METHOD FOR REDUCTION OF FREQUENCY OF INTRAVENTRICULAR HEMORRHAGE IN NEWBORN IN CASE OF EARLY PRETERM DELIVERY, COMPLICATED BY NON-PROGRESSING PLACENTAL ABRUPTION Russian patent published in 2017 - IPC A61K31/195 A61P7/04

Abstract RU 2632711 C1

FIELD: medicine.

SUBSTANCE: from the first minutes, tranexamic acid therapy is provided during admission to the hospital on 25(0)-27(6) weeks of pregnancy for not progressing placental abruption. Hemostatic therapy for patients is performed in the absence of indications for emergency delivery. Hemostatic therapy with tranexamic acid in case of massive (acute) bleeding is prescribed intravenously dropwise for 250-500 mg at a rate of 5-10 mcg/min - 3-4 times a day. The maximum daily dose is 1000-2000 mg/day. Treatment is carried out until the bleeding stops completely, average - 3-4 days. Supportive therapy is prescribed per os 500 mg 3-4 times a day. The maximum daily dose is 1.5-2.0 g, with an average of 3-4 days.

EFFECT: decrease in the frequency of intraventricular hemorrhage in a newborn in case early premature delivery at certain time complicated by non-progressive placental abruption.

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RU 2 632 711 C1

Authors

Kozlov Pavel Vasilevich

Bogaeva Irina Ivanovna

Ilina Irina Yurevna

Dates

2017-10-09—Published

2016-10-12—Filed