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(19)

(11)

2 657 765

(13)

(51)

IPC

A61K35/55(2015-01-01)

A61K38/24(2006-01-01)

A61P15/00(2006-01-01)

(21) (22)

Application

2016124949, 2016-06-21

(24)

Start date

2016-06-21

(22)

Actual filing date

2016-06-21

(45)

Published

2018-06-15

(72)

Inventor

Sein Oleg BorisovichSein Dmitrij OlegovichDurakov Vyacheslav AleksandrovichOlenina Nadezhda Vladimirovna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennaya Selskokhozyajstvennaya Akademiya Imeni I.I. Ivanova"

METHOD FOR OBTAINING A FOLLICLE-STIMULATING HORMONE FROM ANIMAL HYPOPHYSIS Russian patent published in 2018 - IPC A61K35/55 A61K38/24 A61P15/00

Abstract RU 2657765 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry, namely to a method for producing a follicle-stimulating hormone from adenohypophysis of animals. Method for producing a follicle-stimulating hormone from animal adenohypophysis includes homogenizing the adenohypophysis of animals in a buffer solution in the presence of a surfactant Tween-80, ultrasonic effect on the homogenate in the presence of 70% ethanol with a frequency of 20–22 kHz and an intensity of 50–10 W/cm² within 3–5 minutes, release from ballast proteins, isolation, concentration of the hormone using chromatography and freezing.

EFFECT: above-described method allows to increase the yield of follicle-stimulating hormone with high biological activity.

1 cl, 3 tbl, 3 ex

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RU 2 657 765 C1

Authors

Sein Oleg Borisovich

Sein Dmitrij Olegovich

Durakov Vyacheslav Aleksandrovich

Olenina Nadezhda Vladimirovna

Dates

2018-06-15—Published

2016-06-21—Filed