METHOD OF PREVENTING GESTATIONAL COMPLICATIONS IN PREGNANT WOMEN WITH EPILEPSY Russian patent published in 2018 - IPC G01N33/53 A61K38/21 A61P43/00 

Abstract RU 2657772 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology, and can be used to prevent gestational complications in the management of pregnant women with epilepsy. For this at a gestation period of 14–22 weeks, the levels of antibodies to neurospecific proteins are determined: protein S-100, glial fibrillar acid protein (GFAP), myelin basic protein (MBP), nerve growth factor (NGF) in conventional units. When detecting the level of antibodies to these proteins above “0”, designate viferon 1 suppository containing 500,000 ME of the drug, in the rectum for a course of 30 suppositories, at the same time they are administered first 2 times a day after 12 hours for 10 days, then 1 suppository 2 times a day 12 hours 2 times a week.

EFFECT: method allows to prevent gestational complications in pregnant women with epilepsy due to their normalization of their immune status and prevention of neurosensitivity in newborns by reducing the level of neurosensitization of pregnant women, increasing the content of interferons in serum of pregnant women under influence of adequate immunomodulatory therapy.

1 cl, 2 ex

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RU 2 657 772 C1

Authors

Petrukhin Vasilij Alekseevich

Malinovskaya Valentina Vasilevna

Tsivtsivadze Ekaterina Borisovna

Novikova Svetlana Viktorovna

Vlasov Pavel Nikolaevich

Ryazantseva Elena Valerevna

Budykina Tatyana Sergeevna

Bocharova Irina Ivanovna

Dates

2018-06-15Published

2017-07-06Filed