DPA-ENRICHED COMPOSITIONS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS IN FREE ACID FORM Russian patent published in 2018 - IPC A61K31/202 A61K9/48 A61P3/06 A61K45/00 

Abstract RU 2664429 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. Disclosed are: a pharmaceutical composition for the treatment of hypertriglyceridemia and mixed dyslipidemia, comprising EPA (eicosapentaenoic acid) in a weight percentage of 50 to 60%; DHA (docosahexaenoic acid) in a weight percentage of 17 to 23%; DPA (docosapentaenoic acid, 22: 5 n-3) in a weight percentage of 1 to 8%, wherein at least 90% by weight of the polyunsaturated acid in the composition is present in the form of a free acid; a unit dosage form - a capsule for oral administration of said composition and methods for treating hypertriglyceridemia using same (versions).

EFFECT: technical result: significant increase in the bioavailability of the claimed composition in healthy adults (an increase in the EP: AA ratio in blood plasma) compared to a single dose of compositions with ethyl omega-3 acid available on the market.

19 cl, 56 dwg, 40 tbl

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RU 2 664 429 C2

Authors

Mejns Timoti Dzh.

Machils Bernardus N M

Mekhta Bkharat M.

Uajsler Dzherald

Devidson Majkl

Vud Piter Ralf

Dates

2018-08-17Published

2013-01-04Filed