TENOFOVIR PRODRUG AND PHARMACEUTICAL USES THEREOF Russian patent published in 2018 - IPC C07F9/6561 A61K31/675 A61P31/12 

FIELD: chemistry.

SUBSTANCE: invention relates to a compound for the treatment of viral diseases of general formula (I), an enantiomer, diastereomer or a pharmaceutically acceptable salt thereof: , where R¹ and R² are C_1-6-alkyl, respectively, or R¹ and R² together with the attached carbon atom form C_3-7-cycloalkyl, R³ is H or C_1-6-alkyl, Ar represents a substituted or unsubstituted C_6-10-aryl, or 6-10-membered heteroaryl, wherein the substituent is independently selected from alkyl, alkenyl, alkynyl, alkoxy, alkylthio, alkylamino, halogen, thiol, hydroxyl, nitro, cyano, C_3-7-cycloalkyl, C_1-6-aryl, 6-10 membered heteroaryl, including O, S or N as a ring atom.

EFFECT: novel effective antiviral compounds and compositions based thereon have been proposed, that are useful for the treatment of viral infections and for the preparation of medicaments for the treatment of viral infections such as HIV and hepatitis B.

11 cl, 4 tbl, 14 ex