SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS INHIBITORS OF TRK KINASE Russian patent published in 2018 - IPC C07D487/04 A61K31/519 A61P35/00 

Abstract RU 2666367 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a pharmaceutical composition for the treatment of cancer comprising a compound of the formula indicated below, where the cancer is selected from the group consisting of multiple myeloma, lymphoma, breast cancer, prostate cancer, lung cancer, kidney cancer, thyroid cancer, ovarian cancer, pancreatic cancer, colorectal cancer, neuroblastoma, astrocytoma, medulloblastoma, glioma, melanoma, carcinomas of the thyroid gland, adenocarcinoma of the lungs, metastasizing bone disease, neuroendocrine tumor of large cells.

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EFFECT: treatment of cancer.

27 cl, 105 ex

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RU 2 666 367 C2

Authors

Khaas Yuliya

Endryus Stiven U.

Tszyan Yujtun

Chzhan Gan

Dates

2018-09-07Published

2014-05-19Filed