PHARMACEUTICAL ANTITUMORAL COMPOSITION OF PACLITAXEL WITH HISTONE N1.3 AS A CARRIER AND A METHOD FOR PREPARING THE COMPOSITION Russian patent published in 2018 - IPC A61K31/337 A61K47/42 A61P35/00 B82B1/00 B82Y40/00 B01F3/08 

Abstract RU 2669937 C1

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to medicine. Pharmaceutical composition having anti-tumor activity against tumor cells of melanoma M14, prostate cancer PC3 and colorectal carcinoma CaCo2, consisting of paclitaxel and recombinant human histone H1.3 at a mass ratio of histone H1.3 : paclitaxel = 25:1. Method for preparing the above composition by a self-assembly method is proposed.

EFFECT: proposed group of inventions provides creation of safe paclitaxel compositions free from side effects.

2 cl, 5 ex, 2 dwg

Similar patents RU2669937C1

Title Year Author Number
COMPOSITIONS AND METHODS OF DELIVERY OF PHARMACOLOGICAL AGENTS 2009
  • Desaj Nejl P
  • Jang Ehndrju
  • Si Sherri Sjaopehj
  • De Tapas
  • Triu Vuong
  • Soon-Shiong Patrik
  • Bilz Grim Bridzhit
  • Jao Tsjan
RU2522977C2
COMPOSITIONS AND WAYS OF PHARMACOLOGICAL AGENTS DELIVERY 2003
  • Desaj Nejl P.
  • Jang Ehndrju
  • Si Sherri Sjaopehj
  • De Tapas
  • Triu Vuong
  • Soon-Shiong Patrik
  • Bilz Grim Bridzhit
  • Jao Tsjan
RU2361615C2
ANTICANCER TUMOR CISPLATIN COMPOSITION WITH 6-PHOSPHOGLUCONATE DEHYDROGENASE INHIBITOR 2019
  • Minigulova Lejsan Faridovna
  • Savenkova Darya Valerevna
  • Skripova Vera Sergeevna
  • Gavrish Kristina Vladislavovna
  • Nurgalieva Alsina Kamilovna
  • Kiyamova Ramziya Gallyamovna
RU2693004C1
COMPOSITIONS WITH PACLITAXEL, ALBUMIN AND BINDING AGENT AND METHODS FOR THEIR USE AND PREPARATION 2017
  • Markovic, Svetomir N.
  • Nevala, Wendy K.
RU2756892C2
METHOD AND COMPOSITION FOR TREATING CANCER 2011
  • Kabanov Aleksandr V
  • Alakhova Dar'Ja J
  • Zhao Ji
RU2541100C2
COMBINATION AND METHODS FOR INTRODUCING THERAPEUTIC AGENTS AND COMBINED THERAPY 2006
  • Disehj Nejl P.
  • Soon-Shiong Patrik
RU2452482C2
COMBINATIONS AND METHODS FOR THERAPEUTIC AGENTS INTRODUCTION AND COMBINED THERAPY 2012
  • Disej Nejl P.
  • Soon-Shiong Patrik
RU2632103C2
METHODS FOR COMBINATION THERAPY OF PROLIFERATIVE DISEASES 2011
  • Disej Nejl P.
  • Soon-Shiong Patrik
RU2577278C2
MEDICINAL USE OF HISTON DEACETYLASE INHIBITOR AND METHOD FOR ASSAY OF ITS ANTI-TUMOR EFFECT 2002
  • Sasakava Juka
  • Naoe Esinori
RU2298414C2
SUPPRESSION OF CANCER METASTASES 2010
  • Ljan Shu-Mehj
  • Chiu Chin-Fehn
  • Khun Shao-Vehn'
  • Pehn Tszehj-Min
  • Ljan Chi-Min
RU2571502C2

RU 2 669 937 C1

Authors

Chasov Vitalij Vasilevich

Rizvanov Albert Anatolevich

Cheremin Andrej Mikhajlovich

Akhatova Farida Serikovna

Danilushkina Anna Aleksandrovna

Dates

2018-10-17Published

2017-10-17Filed