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2 669 937

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IPC

A61K31/337(2006-01-01)

A61K47/42(2006-01-01)

A61P35/00(2006-01-01)

B82B1/00(2006-01-01)

B82Y40/00(2011-01-01)

B01F3/08(2006-01-01)

(21) (22)

Application

2017136637, 2017-10-17

(24)

Start date

2017-10-17

(22)

Actual filing date

2017-10-17

(45)

Published

2018-10-17

(72)

Inventor

Chasov Vitalij VasilevichRizvanov Albert AnatolevichCheremin Andrej MikhajlovichAkhatova Farida SerikovnaDanilushkina Anna Aleksandrovna

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Federalnyj Universitet" Vo Kfu)

PHARMACEUTICAL ANTITUMORAL COMPOSITION OF PACLITAXEL WITH HISTONE N1.3 AS A CARRIER AND A METHOD FOR PREPARING THE COMPOSITION Russian patent published in 2018 - IPC A61K31/337 A61K47/42 A61P35/00 B82B1/00 B82Y40/00 B01F3/08

Abstract RU 2669937 C1

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to medicine. Pharmaceutical composition having anti-tumor activity against tumor cells of melanoma M14, prostate cancer PC3 and colorectal carcinoma CaCo₂, consisting of paclitaxel and recombinant human histone H1.3 at a mass ratio of histone H1.3 : paclitaxel = 25:1. Method for preparing the above composition by a self-assembly method is proposed.

EFFECT: proposed group of inventions provides creation of safe paclitaxel compositions free from side effects.

2 cl, 5 ex, 2 dwg

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RU 2 669 937 C1

Authors

Chasov Vitalij Vasilevich

Rizvanov Albert Anatolevich

Cheremin Andrej Mikhajlovich

Akhatova Farida Serikovna

Danilushkina Anna Aleksandrovna

Dates

2018-10-17—Published

2017-10-17—Filed